Custom shRNA Screening Libraries

Arrayed or Pooled libraries provide flexible solutions for your screen

SkySilence™ shRNA Arrayed and Pooled Libraries

Skyang Bio provides multiple lentiviral and retroviral vectors for complete flexibility when planning your custom shRNA screen. Our team is dedicated to delivering high-quality, optimized libraries that empower cutting-edge discoveries in functional genomics and therapeutic development. The shERWOOD algorithm is used to design shRNAs or we can use your shRNA designs.  

  • Lentiviral or Retroviral screening libraries are available
  • Target your custom gene list or choose whole genome
  • Provide the number of shRNAs needed for targeting each gene
  • QC is based on NGS to ensure shRNA representation and equal distribution

Deliverable: 

    • Plasmid DNA (Maxiprep or Gigaprep) or ready-to-use lentiviral particles

    • Certificate of analysis showing shRNA distribution according to NGS results

Timeline: As few as 6 weeks for plasmid DNA. Add 2 weeks for lentiviral particles

Request a quote for shRNA 

arrayed or pooled library

Available shRNA Vectors

Lentiviral Vector Options

Retroviral Vector Options

pLMN Vector

pLMP-d Vector

pLMP-d vector schematic

Related Products

Custom NGS and Deconvolution Service – Skyang can help analyze results from your shRNA pooled screening experiments.

Custom Vector Construction Service – Skyang will engineer your next custom vector. Choose from our highly customizable inventory of lentiviral and retroviral cloning vectors. If you need a vector that we currently do not offer, then we can generate that vector for you.

Lentiviral Packaging Service – Skyang lentiviral packaging workflow produces high-quality lentiviral particles. All lentiviral particles are functionally titered, which is the gold standard for quality control.  This facilitates the most precise calculation of MOI for optimized transduction.

Cloning Vectors – Our cloning vectors provide robust modular flexibility, allowing the incorporation of various molecular tags and antibiotic-resistant genes.

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